Dr. Jeffrey Friedman is a physician scientist studying the genetic mechanisms that regulate body weight.
Dr. Friedman's research on various aspects of obesity received national attention in late 1994, when it was announced that he and his colleagues had isolated the mouse ob gene and its human homologue. They subsequently found that injections of the encoded protein, leptin, decreases body weight of mice by reducing food intake and increasing energy expenditure.
Current research is aimed at understanding the genetic basis of obesity in human and the mechanisms by which leptin transmits its weightreducing signal. He is currently a Professor at the Rockefeller University, an Investigator at the Howard Hughes Medical Institute and the Director of the Starr Center for Human Genetics. Dr. Friedman's affiliation with The Rockefeller University began in 1980, where he was awarded a Ph.D. degree in 1986. He was appointed Assistant Investigator with the Howard Hughes Medical Institute at Rockefeller in 1986, promoted to Associate Investigator in 1991, and Investigator in 1997. Dr. Friedman received an MD. degree from Albany Medial College in 1977 and completed a medical residency at Albany Medical College in 1980. Dr. Friedman was born in Orlando, Florida, on July 20, 1954, and grew up in North Woodmere, Long Island. He graduated from Renssalaer Polytechnic Institute magna cum laude and, at the age of 22, received his medical degree from Albany medical College of Union University in Albany, New York.
While at Albany Medical College, he was elected to Alpha Omega Alpha, the medical honor society. After completing a residency in Internal Medicine at Albany Medical Center Hospital, Dr. Friedman came to Rockefeller as a postgraduate fellow and associate physician in 1980. From 1980 to 1981, he also served as a postgraduate fellow at Cornell University Medical College. In 1986, he received a Ph.D. under the tutelage of Professor James E. Darnell, was appointed assistant professor, and became an assistant investigator at the Howard Hughes Medical Institute. Dr. Friedman was appointed Professor at Rockefeller in 1995 after serving as Associate Professor and Head of Laboratory of Molecular Genetics at the Institution since 1991 and in 1998 awarded the Marilyn M. Simpson Professorship. In 1995 he was appointed Director of the Starr Foundation Center for Human Genetics. Dr. Friedman was elected to the National Academy of Science in 2001.
His work was referred to in Time Magazine's Best of Science Section in 1995 and 1996.