Lisa Heather completed an undergraduate degree in Medical Biochemistry at the University of Surrey. She studied for her DPhil in the Department of Physiology, Anatomy and Genetics at the University of Oxford under the supervision of Professor Kieran Clarke, investigating the effects of heart failure on cardiac substrate metabolism and fuel selection. Her postdoctoral research focused on the mitochondria, and how these metabolic organelles can adapt or maladapt in response to cardiac stress.
In 2011, Lisa was awarded an RD Lawrence early career fellowship by Diabetes UK, to set up her own research in Oxford. Her group investigates the metabolic abnormalities that occur in the diabetic heart and whether these contribute to decreased survival following a heart attack. Her current research is focused on novel approaches to manipulate cardiac metabolism as a therapeutic strategy for diabetes. Her group takes a top-down approach to studying metabolism - integrating in vivo physiology, isolated heart perfusion, mitochondrial respiration and molecular biology.